Influence of the fornix section on the biosynthesis of ovarian steroids in the rabbit.

It is now almost undoubtful that in several spieces the hippocampus exerts some influence on the function of pituitary-ovarian axis (Riss et al., 1963; Zarrow et al., 1969; Kling, 1964; Velasco and Taleisnik, 1969; Koikegami et al., 1954). Previous experiments in our laboratory (Kawakami et al., 1967, 1968, 1972) also demonstrated that, in rats and rabbits, the hippocampus is capable of affecting it following the electrical stimulation. However, the physiological significance of the hippocampal function in the maintenance of the functional capacity of ovary has not been evaluated, and this subject is considered to be well dissolved by the elimination of the hippocampal influence to the hypothalamus. The purpose of present study was to know the changes of ovarian biosynthesis, which was indicated by the in vitro transfer rates of 14C from 14C-1-acetate into ovarian hormone